Apply a thin layer to entire face twice a day after cleansing, or spot-apply if you are using another leave-on acne treatment.Using other topical acne drugs at the same time or right after use of this product may increase dryness or irritation of skin. If this occurs, only one medication should be used unless directed by a doctor.Follow with a lightweight, oil-free moisturizer like Dramatically Different Oil-Free Gel.If bothersome dryness or peeling occurs, reduce usage to every other day.LEARN MOREClinique Acne Solutions help get skin clear.Powerful yet gentle routines help get acne under control fast.Dermatological solutions for blackheads are gentle yet effective.Shop Acne Solutions